In another interview with Billboard, Ron Perry, President of Songs Publishing, explained that he wanted Diplo to sign with his company, and in order for this to happen, Diplo had requested that Perry get a "couple rappers" on the track. The producer "put a beat on" and Mars decided to rap. In an interview with Rolling Stone, Diplo explained "Bubble Butt" first began taking shape while he and Bruno Mars were working on material for No Doubt's last album. The song was included in Major Lazer Essentials (2018), their first greatest hits compilation. Major Lazer played the song several times in their shows and in music festivals they performed with 2 Chainz at Coachella, at Rock Werchter in 2013, and at the Roskilde Festival in 2014. The girls start to dance with their new butts after the walls of the apartment fall off and reveal a dancefloor. It depicts three young women in an apartment listening to seapunk music and taking pictures on their phones when a flying giant lands next to their apartment and inflates their buttocks. It has topped the charts in Lebanon and South Korea, and has been certified gold by the Recording Industry Association of America (RIAA).Įric Wareheim of comedy team Tim & Eric directed the song's music video. It was Major Lazer's first commercial single to enter the Billboard Hot 100, peaking at number 56 while reaching number eight on the Dance Club Songs chart. "Bubble Butt" found some commercial success. Some complimented its engaging sound and high energy, while others criticized its lyrical content and repetitious nature. "Bubble Butt" received mixed reviews from most critics. Musically, it is an electronic dance, hip hop, and dancehall track with lyrics implying that girls twerk and show off their giant buttocks. The remix version also features verses from American rapper 2 Chainz. The remix was released as the album's fourth single on May 24, 2013, for digital download and appears on the album's extended version. The production was handled by Major Lazer and Valentino Khan. It was written by Major Lazer members Diplo and Switch alongside the featured artists. " Bubble Butt" is a song by American electronic dance music trio Major Lazer featuring American singer-songwriter Bruno Mars and American rappers Tyga and Mystic from the trio's second studio album, Free the Universe (2013).
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Download AllTrails: Hike, Bike & Run and enjoy it on your iPhone, iPad, and iPod touch. That is, you operate the signals and points/switches in order to get trains to their destinations on time. Search by country to find out where you can make extra savings as you travel. Read reviews, compare customer ratings, see screenshots, and learn more about AllTrails: Hike, Bike & Run. SimSig puts you in the seat of a signaller, also called a Dispatcher or Network Control Officer, operating signalling screens based on the widely used IECC and Westcad graphics used in the UK. Your Pass also gives you discounts and benefits on ferries, buses, attractions and more across Europe. We’ll send them to you by email, so there’s no waiting around. Go online to buy your seat reservations for many popular routes straight from the app. You can choose to only search for trains that accept your Global Pass, and you can see at a glance which trains ask for seat reservations, or you can choose to avoid them altogether. Whether you like to plan in advance or decide on the day, save journeys from the planner to My Trip and see your whole route on the map or as a day-by-day itinerary. rails new myapp create create README.md create Rakefile create create. Whether you’re speeding between cities or taking the scenic route, it’s easy to find trains that match your plans – from local and national trains to high-speed and sleeper services. You can try out Open Rails by downloading this model to drive the route from Edinburgh towards Glasgow. The first argument we'll pass to the rails new command is the application name. Europe at your fingertips Look up train times offline NET, SQL, IIS, VC++ Redistributables and other SDKs. Please note, uninstallation will not remove standalone program entries, such as. Using Command Prompt in administrator mode, go to this directory and run InstallCleanup.exe -f. You should now have access to InstallCleanup.exe from C:\Program Files (x86)\Microsoft Visual Studio\Installer\resources\app\layout\.Then close the Visual Studio Installer window (do not install anything).When prompted to select a workload to install, close the window (do not install anything).Go to /downloads and select a version to download.This tool removes all traces of your previous Visual Studio instance, which is necessary for installing the earlier release. Once uninstallation is complete, you will need to run the Visual Studio Bootstrapper once more so that you can access the InstallCleanup tool. On your Windows desktop machine, go to Add or Remove Programs.If you are unable to follow any of the steps above due to a corrupted install, do the following instead: From Add or Remove Programs, find "Microsoft Visual Studio 2017" and uninstall it.Uninstall every instance of Visual Studio 2017 that you currently have installed and visible in the Visual Studio Installer.On your Windows desktop machine, open the Visual Studio Installer.Microsoft does not guarantee support outside of this policy. Before attempting to modify your current installation of Visual Studio 2017, refer to our support policy, which outlines supported versions. However, approximately 40% of the population carry these alleles and the majority never develop CD. The major genetic risk heterodimer, HLA-DQ2 and DQ8, is already used clinically to help exclude disease. The majority of coeliac disease (CD) patients are not being properly diagnosed and therefore remain untreated, leading to a greater risk of developing CD-associated complications. Romanos, Jihane Rosén, Anna Kumar, Vinod Trynka, Gosia Franke, Lude Szperl, Agata Gutierrez-Achury, Javier van Diemen, Cleo C Kanninga, Roan Jankipersadsing, Soesma A Steck, Andrea Eisenbarth, Georges van Heel, David A Cukrowska, Bozena Bruno, Valentina Mazzilli, Maria Cristina Núñez, Concepcion Bilbao, Jose Ramon Mearin, M Luisa Barisani, Donatella Rewers, Marian Norris, Jill M Ivarsson, Anneli Boezen, H Marieke Liu, Edwin Wijmenga, Cisca Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants. We precompute Envision predictions for every possible single amino acid variant in human, mouse, frog, zebrafish, fruit fly, worm, and yeast proteomes (). Finally, we demonstrate that Envision's performance improves as more large-scale mutagenesis data are incorporated. Envision prediction accuracy is also more consistent across amino acids than other predictors. This dataset was never used for hyperparameter tuning or model training and thus serves as an independent validation set. Envision outperforms other missense variant effect predictors both on large-scale mutagenesis data and on an independent test dataset comprising 2,312 TP53 variants whose effects were measured using a low-throughput approach. Envision combines 21,026 variant effect measurements from nine large-scale experimental mutagenesis datasets, a hitherto untapped training resource, with a supervised, stochastic gradient boosting learning algorithm. Here, we leverage these datasets to develop Envision, which predicts the magnitude of a missense variant's molecular effect. Large datasets describing the quantitative effects of mutations on protein function are becoming increasingly available. Gray, Vanessa E Hause, Ronald J Luebeck, Jens Shendure, Jay Fowler, Douglas M Quantitative Missense Variant Effect Prediction Using Large-Scale Mutagenesis Data. Use of functional assay-based datasets that avoid prior dependencies promises to be valuable for the ongoing development and accurate benchmarking of such tools. Contemporary variant effect prediction tools are unlikely to be as accurate at the general prediction of functional impacts on proteins as reported prior. These results raise concerns about how such algorithms should be employed, particularly in a clinical setting. Benchmarking with the assay-determined datasets UniFun and BRCA1-DMS yielded areas under the receiver operating characteristic curves in the modest ranges of 0.52 to 0.63 and 0.54 to 0.75, respectively, considerably lower than observed for other, potentially more conflicted datasets. Apparent accuracies of variant effect prediction tools were influenced significantly by the benchmarking dataset. Here, we derive three independent, functionally determined human mutation datasets, UniFun, BRCA1-DMS and TP53-TA, and employ them, alongside previously described datasets, to assess the pre-eminent variant effect prediction tools. It is vital that we better understand their accuracies and limitations because published performance metrics are confounded by serious problems of circularity and error propagation. Genetic variant effect prediction algorithms are used extensively in clinical genomics and research to determine the likely consequences of amino acid substitutions on protein function. Mahmood, Khalid Jung, Chol-Hee Philip, Gayle Georgeson, Peter Chung, Jessica Pope, Bernard J Park, Daniel J Variant effect prediction tools assessed using independent, functional assay-based datasets: implications for discovery and diagnostics. This can be illustrated in test render sample (see image 2.0/ Setting 2.1.B and Setting 2.2.B). The shadow in Dome light+ HDRI set-up appears to be smoother than V-Ray sun setting. Follow the parameters set-up I made for this test render experiment (See image 2.1 Dome light Setting). To change the parameters for Dome light follow the procedures: under ‘V-Ray Asset Editor’> go to ‘Lights’> click the V-Ray Dome light> under Light dome, you can see two main parameters (Main and Options). In order to set-up the Dome light: click the Dome light icon and place it in your SketchUp scene. Thus, optimizing the Dome light settings is important in order to produce a suitable environment in relation to HDRI map. Using V-Ray for SketchUp, when loading a Dome light+ HDRI in default setting, the render result will be darker in nature (See image 2.0/ Setting 2.1.A). In comparison to Dome light and V-Ray Environment settings, the shadow appeared to be sharper when rendered using V-Ray Sun and sky system. However, when you turn on the GI Skylight option and choose the V-Ray sky as the light source, the render result will be similar to V-Ray default settings. Under Environment Overrides, the GI Skylight is technically turned off in default settings. If you go to V-Ray Asset Editor> Settings> Environment> Background, you can see that the default background is set to V-Ray Sky or technically the V-Ray Sun (V-Ray sunlight). When set in default setting, notice the sunlight is enabled. In V-Ray default setting, V-Ray Sun and V-Ray Sky are special features which are provided by the V-Ray Renderer. For V-Ray Environment with HDRI texture, the test render will highlight the possible output when render in optimized setting using HDRI as the light source and V-Ray sun as an additional light source. For V-Ray dome light with HDRI texture, a comparison test render was made using default setting and optimized setting. I also added a Sphere model inside the scene with silver polished material in order to see the reflection of the sky.įor V-Ray Sun and Sky System, I set up a basic scene in default setting and lit it a couple of different ways, (enabling and disabling) V-Ray sun, background, and GI (Skylight). In order to fully understand the possible render output in V-Ray using various environment settings such as V-Ray Sun and Sky, Domelight+ HDRI and V-Ray Environment + HDRI, I made a simple rendering experimentation that highlights different parameters or settings which generally affect the tonality and atmosphere of the rendered image output.ĭuring the test render experimentation, I enabled the material override and set the water pool to “Can be Overridden”. Exterior Render Settings (V-Ray 3.4 for SketchUp)Įxterior Render Settings V-Ray and SketchUp (kay SWAY/nyez kohn lohss ang/hay/LEE/tohss) Sweet dreams. (Oh/RAH day Door/MEEHR) It's time for bed. (Ray/CO/heh twos who/GET/ehs) Clean up your toys. (Say/PEE/yatch/eh laws Dee/EHN/tehs) Brush your teeth. Once your child understands what the Spanish phrase means, use only that version every day. Start by using the Spanish phrase directly followed by the English translation. This is an easy Printable Numbers Handwriting activity pages for preschoolers and kindergarten kids to trace, count, and learn numbers in Spanish. (see/EH/rrah lah poo/ER/tah) Close the door.Īdding a few basic Spanish phrases for kids to learn in home routines is an easy way to practice and master common phrases. These revised pre-kindergarten to grade 12 standards are based on research and effective practice, and will enable teachers and administrators to strengthen. (may TOE/kah…tay TOE/kah) It's my turn…it's your turn. (may GOOSE/tah…may eng/KAHN/tah) I like it…I love it. (diss/KOOL/pah…kohn pear/MEE/soh) Sorry…excuse me. ¿Quieres más? (kee/AIR/ess MAHS) Do you want more?.(ess OR/ah day koh/MARE) It's time to eat. ¿Tienes hambre? (tee/EN/ez AHM/bray) Are you hungry?.❽ónde estás? (DON/day ess/TAHSS) Where are you?.(BEHN ah/CA…see/EN/tah/tay) Come here…sit down. (POR fah/VOR…day NAH/da) Please…thank you. Add these fast phrases to your family or classroom conversations: Students in kindergarten through 12th grade are required to be immunized with DTaP/Tdap, polio, MMR, Hepatitis B, and Varicella vaccines. Once a phrase or two is mastered, make it your default for an activity like having supper or tucking el angelito (elle ang/hay/LEE/toh), the little angel, in at night. Teach related phrases in groups that are simpler to remember than random remarks. Keep it short and sweet for good retention and polite, practical conversation with kids. Spanish Courtesies and Conversation Phrases for Kids To learn more about managing and updating Remote Config parameters and You can do this before or after you launch your app,īecause the same get methods access in-app default valuesĪnd values fetched from the Remote Config backend. You can define values in the Firebase console or the Remote Configĭefault values. (As needed) Update server-side default and conditional parameter values Get the value of a parameter, similar to reading the value of a local Without worrying about the best time to fetch values, or even whether any New Remote Config version is published without the need for polling. Real-time Remote Config lets your apps fetch updated values as soon as a Remote Config backend periodically and activate those fetched values. Your app can safely and efficiently fetch parameter values from the Set the in-app default values for Remote Config parameters usingĪdd logic to fetch, activate, and get parameter values Parameters that you will use in your app. Implementation pathĭefine which aspects of your app's behavior and appearance you want toīe able to change using Remote Config, and translate these into the Resolves conflicts between conditional values, see To learn more about parameters, conditions, and how Remote Config Parameter, you can set a server-side default value to override the in-appĭefault value, and you can also create conditional values to override the in-appĭefault value for app instances that meet certain conditions. Parameters with the same names as the parameters used in your app. Or the Remote Config backend APIs to create To override in-app default values, you use the Firebase console The same logic it uses to get in-app default values, so you can add theĬapabilities of Remote Config to your app without writing a lot of code. The Remote Config client library get methods provide a single access Remote Config parameter values as soon as they're published. This lets you safeguard your app experience by controlling theįunctionality to your fetch logic to automatically fetch the latest You control over when new values are activated so that they affect your app's Remote Config includes a client library that handles important tasks likeįetching parameter values and caching them, while still giving Improvements before rolling them out to your entire user base. To your app across different segments of your user base to validate Percentage targeting with Google Analytics to A/B test improvements Optimize for goals like user engagement, ad clicks, and revenue-or anyĬustom event you can measure with Google Analytics-with Use machine learning to continuously tailor individual user experience to Use Remote Config personalization to automatically and continuouslyĬustomize your app for individual users and optimize for strategic goals You can use Remote Config to provide variations on your app's userĮxperience to different segments of your user base by app version, language, Remote Config parameter as a feature flag to change your app's layout orĬolor theme to support a seasonal promotion, with no need to publish an appĬustomize your app for segments of your user base You can make changes to your app's default behavior and appearance byĬhanging server-side parameter values. IOS+ setup Android setup Web setup Flutter setup C++ setup Unity setup Backend APIs Key capabilities Quickly roll out changes to your app's user base YourĪpp controls when updates are applied, and it can frequently check for updatesĪnd apply them with a negligible impact on performance. In-app default values for all app users or for segments of your user base. Use the Firebase console or the Remote Config backend APIs to override Values that control the behavior and appearance of your app. When using Remote Config, you create in-app default Firebase Remote Config is a cloud service that lets youĬhange the behavior and appearance of your app without requiring users toĭownload an app update. Specified time frame (most of the time it is instant) Once the payment is confirmed, a chat room will appear where you canĭepending on the delivery time, you will be receiving your Runescape account details in Offer to make sure everything works for youĬlick „Buy Now“ button and make a payment with your preferred payment Look through the listed Runescape 3 accounts and pick the one Looking to buy RS3 accounts? Here’s a quick guide how to get started: You as a seller are protected by TradeShield protection. After verifying your ID, which we require due to increased risk involved in buying RS Accounts, you can place your offer online. Selling your Runescape Account with Eldorado.gg is very easy and fast. Finally, the headache of buying and selling Runescape accounts can be avoided right here. On the marketplace for gamers, buyers and sellers are rated in order to protect both parties. On Eldorado.gg no one has to worry about any of these issues. 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This is some sort of bonus program that Windows Update may install if you have a Microsoft branded mouse or keyboard (possibly on your behalf) that as far as I can tell offers little meaningful functionality over standard Windows mouse options, especially if your mouse / keyboard is a basic one. This can be found in your Windows Control Panel's normal uninstall page. Uninstall 'Microsoft Mouse and Keyboard Center'. There is another solution if your media keys refuse to work without VLC being the focused application: The information is useful for someone setting up VLC media key functionality for the first time but a bit of browsing around suggests that this problem persists for some people even after setting their hot key preferences. both have same hot key effect.This page seems to be the top result for this problem when Googling "vlc media keys not working", however the top (and only) answer doesn't actually address the problem. 10% less, 2 = normal, 3 = faster, 5 = frame by frame & I map arrow keys to skip & to in/out of full screen.īut it is true that VLC does not distinguish numbers above querty keys from numpad numbers. I mostly map the number pad to speed changes: 1 = slower (fine) i.e. My cyberlink remotes have a numpad secion but the 0 thru 9 buttons can't be reprogrammed, so I make use of 0 thu 9 in various VLC hotkey settingsĮ.g. I have to have windows next/prev task keys assigned & working for when VLC is not in focus & cycle thru them to get it back. The most annoying feature of VLC is this scenario is that it has so many ways of losing focus yet continuing to play in background, so regaining control with the remote is a nightmare. then I tweak VLC hot keys to get the layout I want. the intelliremote program lets me assign any key to any button on my remote, & it distinguishes 1 2 3. I use vlc with a remote control + intelliremote software. There are still keys that it won't let you assign as shortcuts, so you just have to opt for ones it will accept.īTW, I think "media keys" means those extra keys on your keyboard that are labelled as if they are supposed to do all the stopping and starting, but actually don't work. This speeds up the process of transcribing audio unbelievably. Result - time consuming constant swapping and losing your place in the document if transcribing audio.)įor reference I am running OpenOffice writer and VLC on Linux( Uberstudent), and I can now listen to an audio recording with a text document open, and stop and start, back track and slow down by pressing short-cut keys, but without having to quit the active text window. (Prior to making that change, I had precisely the problem that the new shortcut keys worked when the VLC window was active, but as soon as I clicked in to type some text in a document they were disactivated. What ever that means I don't know, but it works. So now it looks like it is unassigned as a hotkey but assigned as a "global". Simply, you have to assign your new shortcut key in the "global" column, but you must remove the corresponding entry under the "hotkey" column (immediately to the left). Actually it was ( for me anyway) what made all the difference. But what made the difference for me was the other bit of advice that the previous poster mentioned but thought " probably didn't make any difference". If you are doing a lot of trial and error you can forget one time to restart it again - and maybe then miss the one time you actually ticked all the right boxes.īut you said you had done that. One is that every single time you make a change to the settings you must restart VLC. It seems to me there are two steps you have to get right. I've just spent half a morning playing with this problem, and am so delighted to have found the answer that I've joined the forum just to add my two pennyworth. There is also space to take note of the day’s weather, as well as one’s mood. You can circle the appropriate name for the day’s entry. Near the top of the page are the names of the days of the week. Looking for more examples of journal templates that kids can use? Here’s another one that allows you and your child to document what happened during the day and reflect on it. As you start this habit, you will be surprised at how it can drastically change your life, perception, and views. These are just some of the benefits of keeping a daily journal. When you see how much they have contributed to your growth as a person, you will feel more affection for them. Keeping a journal also allows you to rethink and reevaluate your relationships with the people around you. Seeing your plans and the things you have done laid out in plain sight can make you appreciate yourself and the people around you even more. This is why journals are great tools to help learn the art of gratitude and recognition. Develops a person’s sense of gratitude and appreciation.Ī daily journal will often include things that you appreciate and are grateful for. When your life is organized and your emotions are clear, you feel less worried about how to handle difficult situations when they arise. It is a therapeutic and peaceful way to let go of your emotions whenever you feel them about to overflow. Writing is one of the best ways to release all of your tension and pent-up anxiety. Releases stress and clears your emotions. Having a journal helps you achieve that peace of mind you’ve been longing for so. You also don’t have to waste time remembering when the next office meeting is, or the deadline for a particular project. You don’t have to think about where you put the sticky note with your assignment written on it. When you keep a journal with daily entries, your thoughts are all stored in one place. Keeps your mind clear and your thoughts organized. In addition, it boosts creativity and inspires you to follow through with your plans. Keeping a daily journal isn’t just for fun and recreation-it is actually a tool to make you more productive and hardworking, and help you accomplish your tasks and achieve your goals. Reasons to Keep a Daily Journal Maximizes your creativity and productivity. BirchTree Organizing Printable Daily Planner 19 Personal Daily Journal Template Examples.Develops a person’s sense of gratitude and appreciation.Releases stress and clears your emotions.Keeps your mind clear and your thoughts organized.Maximizes your creativity and productivity. |
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